Fhe Gene Detail

Summary

• Symbol
  Fhe
• Name
  Friend helper virus erythroblastosis susceptibility

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95532
  NCBI Gene: 108032
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Mutations,
Alleles, and
Phenotypes

This locus controls development of erythroblastosis induced by helper virus component of Friend NB-tropic virus. The r allele determines resistance in C57BL/6 and B10.D2 strains; the s allele determines susceptibility in BALB/c. F1 mice are resistant.

Sequences &
Gene Models

• NCBI Gene
  108032

Other
Accession IDs

MGD-MRK-9795

References

• Summaries
  All 3
• Earliest
  J:7176 Silver JE, et al., A new gene that controls the type of leukemia induced by Friend murine leukemia virus. J Exp Med. 1983 Aug 1;158(2):493-505
• Latest
  J:7221 Silver JE, et al., Susceptibility to Friend helper virus leukemias in CXB recombinant inbred mice. J Exp Med. 1983 Nov 1;158(5):1693-702