gnd Gene Detail

Summary

• Symbol
  gnd
• Name
  generalized neuroaxonal dystrophy

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95786
  NCBI Gene: 14698
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome Unknown

Human Diseases

• Diseases
  1 with gnd mouse models

Human Disease

Mouse Models

neurodegeneration with brain iron accumulation 2a

IDs

neurodegeneration with brain iron accumulation 2a      

DOID:0110735
ICD10CM:G23.0
OMIM:256600

View 1 model

Mouse Models

Human Disease Modeled: neurodegeneration with brain iron accumulation 2a

Allelic Composition	Genetic Background	Reference	Phenotypes
gnd/gnd	C3H/HeJ-gnd	J:11718	View

Click on a disease name to see all genes associated with that disease.

• Mutations/Alleles
  1 with disease annotations

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for a spontaneous mutation breed only rarely, display a dull hair coat and small body size, and progressively develop a hunched posture, shaky gait and hindlimb paralysis associated with generalized neuroaxonal dystrophy.

Sequences &
Gene Models

• NCBI Gene
  14698

Other
Accession IDs

MGD-MRK-10205

References

• Summaries
  All 2

  Diseases 1

  Phenotypes 1
• Earliest
  J:11718 Bronson RT, et al., Genetic and age related models of neurodegeneration in mice: dystrophic axons. J Neurogenet. 1992 May;8(2):71-83