Gv1 Gene Detail

Summary

• Symbol
  Gv1
• Name
  Gross virus antigen 1
• Synonyms
  Gv-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:95877
  NCBI Gene: 109831
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 13, Syntenic
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• Find Mice (IMSR)
  0 strains or lines available

Gv1 and Gv2 control GIX antigen on thymocytes of mice with positive alleles at both loci. Allele a (presence of GIX) is seen in 129, CE, AKR, SJL, DBA/2, C3H/An, 101, C58, A and I; allele b (absence) in C57BL strains, BALB/c, CBA/J, RF/J, MA/J and SWR. Heterozygotes have half the amount of antigen.

Sequences &
Gene Models

• NCBI Gene
  109831

Other
Accession IDs

MGD-MRK-10338, MGD-MRK-10340

References

• Summaries
  All 11

  Phenotypes 1
• Earliest
  J:5335 Ikeda H, et al., Relation of chromosome 4 (linkage group 8) to murine leukemia virus-associated antigens of AKR mice. J Exp Med. 1973 Apr 1;137(4):1103-7
• Latest
  J:343949 Young GR, et al., Gv1, a Zinc Finger Gene Controlling Endogenous MLV Expression. Mol Biol Evol. 2021 May 19;38(6):2468-2474