H2-Q3 Pseudogene Detail

Summary

• Symbol
  H2-Q3
• Name
  histocompatibility 2, Q region locus 3
• Synonyms
  Qa3

• Feature Type
  pseudogene
• IDs
  MGI:95932
  NCBI Gene: 625285
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr17:35577965-35578948 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, 18.64 cM, cytoband B-C
• Mapping Data
  8 experiments

Strain
Comparison

• SNPs within 2kb
  1 from dbSNP Build 142
• Strain Annotations
  14

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_95932	pseudogene	Chr17:35577945-35578958 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0040163	pseudogene	Chr17:35516578-35517561 (+)
A/J	MGP_AJ_G0040103	pseudogene	Chr16:37984485-37985470 (+)
AKR/J	MGP_AKRJ_G0040077	pseudogene	Chr17:34825747-34826733 (+)
BALB/cJ	no annotation
C3H/HeJ	MGP_C3HHeJ_G0039787	pseudogene	Chr17:35184519-35185501 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0040731	pseudogene	Chr17:36904411-36905394 (+)
CAROLI/EiJ	no annotation
CAST/EiJ	MGP_CASTEiJ_G0038875	pseudogene	Chr17:35242853-35243844 (+)
CBA/J	MGP_CBAJ_G0039752	pseudogene	Chr17:38513532-38514514 (+)
DBA/2J	MGP_DBA2J_G0039938	pseudogene	Chr17:32139177-34455482 (-)
FVB/NJ	no annotation
LP/J	MGP_LPJ_G0039994	pseudogene	Chr17:35872053-35873036 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0039899	pseudogene	Chr17:37312883-37313866 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0040830	pseudogene	Chr17:35080559-35081543 (+)
PWK/PhJ	MGP_PWKPhJ_G0038568	pseudogene	Chr17:32711076-32712065 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0038272	pseudogene	Chr17:33201735-33202721 (+)
WSB/EiJ	no annotation

Homology

• Gene Tree
  H2-Q3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  1
• Targeted
  1
• Genomic Mutations
  1 involving H2-Q3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  4 strains or lines available

This locus controls a serologically detected antigen limited predominantly Thy1+ cells of lymph node and spleen. The a allele determines presence of antigen in BALB/cJ, C56BL/6, and A; the b allele determines absence of antigen in DBA/1 and SWR.

Expression

• Assay Results
  706

Tissue x Stage Matrix

• Other Mouse Links
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  18
• RefSeq
  1

• Ensembl
  ENSMUSG00000092253 (Evidence)
• NCBI Gene
  625285

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000092253	Ensembl Gene Model | MGI Sequence Detail	984	C57BL/6J
transcript	ENSMUST00000172583	Ensembl | MGI Sequence Detail	608	Not Applicable

Molecular
Reagents

• All nucleic 5

  Genomic 4

  Other 1

Other
Accession IDs

MGD-MRK-10415, MGD-MRK-10528, MGD-MRK-13711, MGD-MRK-13722, MGI:3644098

References

• Summaries
  All 19

  Phenotypes 1
• Earliest
  J:4437 Flaherty L, et al., Further seriological analysis of the Qa antigens: analysis of an anti-H-2.28 serum. Immunogenetics. 1978;6:245-251
• Latest
  J:190754 Ermakova O, et al., Construction and phenotypic analysis of mice carrying a duplication of the major histocompatibility class I (MHC-I) locus. Mamm Genome. 2012 Aug;23(7-8):443-53

TSS for H2-Q3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr144360	Chr17:35577945-35577965 (+)	-10 bp