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Selenos Gene Detail
Summary
  • Symbol
    Selenos
  • Name
    selenoprotein S
  • Synonyms
    1500011E07Rik, C78786, H-4, H4, H-47, H47, Seps1, Vimp
  • Feature Type
    protein coding gene
  • IDs
    MGI:95994
    NCBI Gene: 109815
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:65729397-65739153 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 35.49 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    383 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_95994
 protein coding gene Chr7:65729397-65739153 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032348
 protein coding gene Chr7:67299411-67309091 (+)
A/J MGP_AJ_G0032327
 protein coding gene Chr7:65922803-65932361 (+)
AKR/J MGP_AKRJ_G0032263
 protein coding gene Chr7:67322583-67332314 (+)
BALB/cJ MGP_BALBcJ_G0032339
 protein coding gene Chr7:65653253-65663038 (+)
C3H/HeJ MGP_C3HHeJ_G0032052
 protein coding gene Chr7:67991569-68002187 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032832
 protein coding gene Chr7:70201069-70211730 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029839
 protein coding gene Chr7:68822087-68832084 (+)
CAST/EiJ MGP_CASTEiJ_G0031381
 protein coding gene Chr7:58668361-58678033 (+)
CBA/J MGP_CBAJ_G0032018
 protein coding gene Chr7:72382194-72391935 (+)
DBA/2J MGP_DBA2J_G0032174
 protein coding gene Chr7:64637864-64647893 (+)
FVB/NJ MGP_FVBNJ_G0032128
 protein coding gene Chr7:64771353-64781073 (+)
LP/J MGP_LPJ_G0032254
 protein coding gene Chr7:68514485-68524027 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032165
 protein coding gene Chr7:72633216-72644041 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032849
 protein coding gene Chr7:66671709-66682283 (+)
PWK/PhJ MGP_PWKPhJ_G0031101
 protein coding gene Chr7:57672354-57682104 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030942
 protein coding gene Chr7:53733836-53743689 (+)
WSB/EiJ MGP_WSBEiJ_G0031499
 protein coding gene Chr7:67002522-67013108 (+)



Homology
more
  • Human Ortholog
    SELENOS, selenoprotein S
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SELENOS, selenoprotein S
  • Synonyms
    AD-015, ADO15, SBBI8, SELS, SEPS1, VIMP
  • Links
    NCBI Gene ID: 55829
    neXtProt AC: NX_Q9BQE4
    UniProt: Q9BQE4

  • Chr Location
    15q26.3; chr15:101270809-101277500 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    7 phenotypes from multigenic genotypes
    22 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice heterozygous or homozygous for a knock-out allele exhibit impaired contractile function of fast-twitch hindlimb muscles.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    55
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    769
  • Tissues
    14
  • cDNA Data
    140
  • Literature Summary
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 109815 NCBI Gene Model | MGI Sequence Detail 9757 C57BL/6J ±  kb
    transcript NM_001348246 RefSeq | MGI Sequence Detail 1237 ZRU/MplStud  
    polypeptide Q9BCZ4 UniProt | EBI | MGI Sequence Detail 190 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 142
      cDNA 141
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-10460, MGD-MRK-10468, MGD-MRK-10590, MGI:1916234, MGI:2142327
    References
    more
    • Summaries
      All 63
      Developmental Gene Expression 6
      Gene Ontology 8
      Phenotypes 22
    • Earliest
      J:121 SNELL GD, et al., Histocompatibility genes of mice. III. H-1 and H-4, two histocompatibility loci in the first linkage group. Immunology. 1961 Oct;4:366-79
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory