Hivep1 MGI Mouse Gene Detail - MGI:96100 - human immunodeficiency virus type I enhancer binding protein 1

Symbol

Hivep1
Name

human immunodeficiency virus type I enhancer binding protein 1
Synonyms

alphaA-CRYBP1, Cryabp1

Feature Type

protein coding gene
IDs

MGI:96100
NCBI Gene: 110521
Alliance

gene page
Transcription Start Sites

11 TSS

Sequence Map

Chr13:42205304-42338504 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 20.72 cM
Mapping Data

7 experiments

SNPs within 2kb

2710 from dbSNP Build 142
Strain Annotations

18
RFLP

2

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_96100	protein coding gene	Chr13:42205304-42346013 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020493	protein coding gene	Chr13:40577020-40709366 (+)
A/J	MGP_AJ_G0020447	protein coding gene	Chr13:39220643-39348506 (+)
AKR/J	MGP_AKRJ_G0020425	protein coding gene	Chr13:40300858-40432888 (+)
BALB/cJ	MGP_BALBcJ_G0020443	protein coding gene	Chr13:39418600-39555209 (+)
C3H/HeJ	MGP_C3HHeJ_G0020242	protein coding gene	Chr13:40162321-40299206 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0020876	protein coding gene	Chr13:41860321-41995795 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018463	protein coding gene	Chr13:37327019-37457214 (+)
CAST/EiJ	MGP_CASTEiJ_G0019757	protein coding gene	Chr13:39968686-40099452 (+)
CBA/J	MGP_CBAJ_G0020203	protein coding gene	Chr13:43649590-43787092 (+)
DBA/2J	MGP_DBA2J_G0020325	protein coding gene	Chr13:38781695-38909884 (+)
FVB/NJ	MGP_FVBNJ_G0020304	protein coding gene	Chr13:38293989-38429213 (+)
LP/J	MGP_LPJ_G0020400	protein coding gene	Chr13:40825578-40962220 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020333	protein coding gene	Chr13:43587280-43730152 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0020919	protein coding gene	Chr13:39954266-40087562 (+)
PWK/PhJ	MGP_PWKPhJ_G0019512	protein coding gene	Chr13:38874351-39003397 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019342	protein coding gene	Chr13:38583816-38710325 (+)
WSB/EiJ	MGP_WSBEiJ_G0019819	protein coding gene	Chr13:40253082-40388879 (+)

Human Ortholog

HIVEP1, HIVEP zinc finger 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

HIVEP1, HIVEP zinc finger 1
Synonyms

CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A
Links

HGNC:4920

NCBI Gene ID: 3096

neXtProt AC: NX_P15822

UniProt: P15822
Chr Location

6p24.1; chr6:12007693-12212048 (+) GRCh38

MGI Vertebrate Homology

Hivep1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: HIVEP1
Gene Tree

Hivep1

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Phenotype Summary

6 phenotypes from 1 allele in 1 genetic background
13 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

3
Targeted

3
Genomic Mutations

1 involving Hivep1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

105 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

20
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

838
Tissues

93
cDNA Data

89
Literature Summary

7

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase hivep1

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All Sequences

53
RefSeq

10
UniProt

8
CCDS

CCDS36643.1

Ensembl

ENSMUSG00000021366 (Evidence)
NCBI Gene

110521

			Length	Strain/Species	Flank
genomic	110521	NCBI Gene Model \| MGI Sequence Detail	133201	C57BL/6J	± kb
transcript	NM_007772	RefSeq \| MGI Sequence Detail	8753	Not Specified
polypeptide	Q03172	UniProt \| EBI \| MGI Sequence Detail	2688	Not Applicable

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UniProt

8 Sequences
Protein Ontology

PR:000008604 zinc finger protein 40

(term hierarchy)
InterPro Domains

IPR003604 Matrin/U1-C-like, C2H2-type zinc finger

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

IPR034729 Zinc finger CCHC HIVEP-type

IPR051969 Zinc-finger DNA-binding transcription regulators
GlyGen

Q03172 12 sites, 1 O-linked glycan (12 sites)

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All nucleic 99

Genomic 6

cDNA 92

Primer pair 1

Microarray probesets 3

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MGD-MRK-10732, MGD-MRK-2164, MGI:88517

Summaries

All 52

Developmental Gene Expression 7

Gene Ontology 7

Phenotypes 13
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Hivep1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr119426	Chr13:42204760-42204798 (+)	-525 bp
Tssr119427	Chr13:42205224-42205249 (+)	-67 bp
Tssr119428	Chr13:42205318-42205351 (+)	31 bp
Tssr119429	Chr13:42205472-42205483 (+)	174 bp
Tssr119430	Chr13:42205491-42205548 (+)	216 bp
Tssr119431	Chr13:42205588-42205604 (+)	292 bp
Tssr119432	Chr13:42205792-42205844 (+)	514 bp
Tssr119433	Chr13:42206486-42206498 (+)	1,188 bp
Tssr119434	Chr13:42223138-42223142 (+)	17,836 bp
Tssr119435	Chr13:42256632-42256672 (+)	51,348 bp
Tssr119436	Chr13:42302828-42302831 (+)	97,526 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24