Hm Cytogenetic Marker Detail

Summary

• Symbol
  Hm
• Name
  hammer toe

• Feature Type
  insertion
• IDs
  MGI:96110
  NCBI Gene: 109572

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  32 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  3 phenotypes from multigenic genotypes
  2 images
  18 phenotype references
  

• All Mutations and Alleles
  3
• Endonuclease-mediated
  2
• Spontaneous
  1
• Find Mice (IMSR)
  3 strains or lines available

Mutations in this gene result in abnormal development of the feet.

Sequences &
Gene Models

• NCBI Gene
  109572

Other
Accession IDs

MGD-MRK-10744

References

• Summaries
  All 34

  Phenotypes 18
• Earliest
  J:5602 Womack JE, et al., Mitochondrial malate dehydrogenase (Mor-1) in the mouse: linkage to chromosome 5 markers. Biochem Genet. 1975 Oct;13(9-10):519-25
• Latest
  J:257769 Paliou C, et al., Large genomic insertion at the Shh locus results in hammer toes through enhancer adoption. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):839-841