Hoxc Complex/Cluster/Region Detail

Summary

• Symbol
  Hoxc
• Name
  homeobox C cluster
• Synonyms
  Hox-3, Hox-6

• Feature Type
  complex/cluster/region
• IDs
  MGI:96191
  NCBI Gene: 111339
• Cluster Members
  Hoxc13, Hoxc12, Hoxc11 ... (9 members)

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 15, cytoband F1-F3
• Mapping Data
  13 experiments

Strain
Comparison

• PCR
  5
• RFLP
  1

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  11 phenotypes from 1 allele in 1 genetic background
  9 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  4
• Targeted
  2
• Find Mice (IMSR)
  1 strains or lines available

Targeted deletion of the Hoxc gene cluster results in neonatal lethality.

Sequences &
Gene Models

• NCBI Gene
  111339

Molecular
Reagents

• All nucleic 3

  Genomic 2

  Primer pair 1

Other
Accession IDs

MGD-MRK-10838, MGD-MRK-10864, MGD-MRK-10892

References

• Summaries
  All 38

  Phenotypes 9
• Earliest
  J:8243 Awgulewitsch A, et al., Spatial restriction in expression of a mouse homoeo box locus within the central nervous system. Nature. 1986 Mar 27-Apr 2;320(6060):328-35
• Latest
  J:297683 Fernandez-Guerrero M, et al., Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30509-30519

Hoxc Cluster contains:

More Data for these features

Member	Feature Type	Location
Hoxc13, homeobox C13	protein coding gene	Chr15:102829566-102837249 (+)
Hoxc12, homeobox C12	protein coding gene	Chr15:102845261-102847044 (+)
Hoxc11, homeobox C11	protein coding gene	Chr15:102862961-102865136 (+)
Hoxc10, homeobox C10	protein coding gene	Chr15:102875231-102880328 (+)
Hoxc9, homeobox C9	protein coding gene	Chr15:102885467-102893324 (+)
Hoxc8, homeobox C8	protein coding gene	Chr15:102899039-102902543 (+)
Hoxc6, homeobox C6	protein coding gene	Chr15:102906689-102920313 (+)
Hoxc5, homeobox C5	protein coding gene	Chr15:102922440-102925861 (+)
Hoxc4, homeobox C4	protein coding gene	Chr15:102927366-102945278 (+)