Hsdr1 Gene Detail

Summary

• Symbol
  Hsdr1
• Name
  hepatocyte specific developmental regulation 1
• Synonyms
  albino-lethal factor, alf, Alf, hsdr-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96237
  NCBI Gene: 110773
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 7, Syntenic
• Mapping Data
  4 experiments

Strain
Comparison

• RFLP
  8

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  8 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Genomic Mutations
  1 involving Hsdr1
• Find Mice (IMSR)
  0 strains or lines available

Mutations in this gene result in lethality due to hypoglycemia.

Sequences &
Gene Models

• NCBI Gene
  110773

Molecular
Reagents

• All nucleic 42

  Genomic 24

  Other 18

Other
Accession IDs

MGD-MRK-10950, MGD-MRK-10951, MGD-MRK-1280

References

• Summaries
  All 14

  Phenotypes 8
• Earliest
  J:5435 Gluecksohn-Waelsch S, et al., Complementation studies of lethal alleles in the mouse causing deficiencies of glucose-6-phosphatase, tyrosine aminotransferase, and serine dehydratase. Proc Natl Acad Sci U S A. 1974 Mar;71(3):825-9
• Latest
  J:16987 Holdener BC, et al., A mouse model for human hereditary tyrosinemia I. Bioessays. 1994 Feb;16(2):85-7