Hst6 Gene Detail

Summary

• Symbol
  Hst6
• Name
  hybrid sterility 6

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96263
  NCBI Gene: 109729
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr17:29710019-31900698 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 17, Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

This locus is one of several showing hybrid sterility phenotype and mapping to proximal Chromosome 17. Homozygotes for the sterility allele show morphological abnormality in the curvature of sperm flagella. The Hst6 product appears to be important in assembly and function of the sperm axoneme.

Sequences &
Gene Models

• NCBI Gene
  109729

Other
Accession IDs

MGD-MRK-10986

References

• Summaries
  All 7
• Earliest
  J:14817 Pilder SH, et al., Hybrid sterility-6: a mouse t complex locus controlling sperm flagellar assembly and movement. Dev Biol. 1993 Oct;159(2):631-42
• Latest
  J:101666 Samant SA, et al., The mouse t complex distorter/sterility candidate, Dnahc8, expresses a gamma-type axonemal dynein heavy chain isoform confined to the principal piece of the sperm tail. Dev Biol. 2005 Sep 1;285(1):57-69