Igk-Ef2 Gene Detail

Summary

• Symbol
  Igk-Ef2
• Name
  immunoglobulin kappa chain Ef2

• Feature Type
  gene segment
• IDs
  MGI:96496
  NCBI Gene: 110205
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 6, Syntenic
• Mapping Data
  6 experiments

Mutations,
Alleles, and
Phenotypes

Strain variation is seen by isoelectric focusing: BALB/c, AKR and C57BL/6 (a allele) display bands; NZB, BDP, CE, I/Ln, P/J and C58 (b allele) do not. DNA analysis with a V-kappa1A probe divide b allele strains: BDP, CE, I/Ln and P/J show the same BamHI bands as a allele strains; NZB and C58 do not.

Sequences &
Gene Models

• NCBI Gene
  110205

Other
Accession IDs

MGD-MRK-11295

References

• Summaries
  All 7
• Earliest
  J:6146 Gibson DM, et al., Ef2: a new LY-3-linked light-chain marker expressed in normal mouse serum immunoglobulin. J Exp Med. 1979 Jun 1;149(6):1477-86
• Latest
  J:17774 Primi D, et al., Structural polymorphism of V kappa 21 E and V kappa 21 D gene products in laboratory mice. Eur J Immunol. 1986 Mar;16(3):292-6