Len1 Gene Detail

Summary

• Symbol
  Len1
• Name
  eye lens protein 1
• Synonyms
  Len-1

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96771
  NCBI Gene: 109715
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 1, Syntenic
• Mapping Data
  13 experiments

Mutations,
Alleles, and
Phenotypes

Len1 encodes a 22kDa major lens protein of the gamma-crystallin class, synthesized from embryonic day 14 to postnatal week 4. Variation is seen by isolelectric focusing: the a allele in DBA/2; b allele in BALB/c, C57BL/6, C57BL/10 and SEC/1; c allele in M.m. molossinus and M.m. castaneus.

Sequences &
Gene Models

• NCBI Gene
  109715

Other
Accession IDs

MGD-MRK-11784, MGD-MRK-11786

References

• Summaries
  All 18
• Earliest
  J:6755 Skow LC, Location of a gene controlling electrophoretic variation in mouse gamma-crystallins. Exp Eye Res. 1982 Apr;34(4):509-16
• Latest
  J:60856 Smith RS, et al., Lop12, a mutation in mouse Crygd causing lens opacity similar to human Coppock cataract. Genomics. 2000 Feb 1;63(3):314-20