lgl Gene Detail

Summary

• Symbol
  lgl
• Name
  legless

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96780
  NCBI Gene: 16862
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, Syntenic
• Mapping Data
  3 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  18 phenotypes from 1 allele in 1 genetic background
  14 phenotypes from multigenic genotypes
  11 phenotype references
  

• All Mutations and Alleles
  1
• Transgenic
  1
• Find Mice (IMSR)
  0 strains or lines available

Mutations in this gene result in limb deformities and craniofacial and brain abnormalities resulting in neonatal death.

Sequences &
Gene Models

• NCBI Gene
  16862

Molecular
Reagents

• All nucleic 5

  Genomic 5

Other
Accession IDs

MGD-MRK-11799

References

• Summaries
  All 14

  Phenotypes 11
• Earliest
  J:9298 McNeish JD, et al., Legless, a novel mutation found in PHT1-1 transgenic mice. Science. 1988 Aug 12;241(4867):837-9
• Latest
  J:86196 Bell SM, et al., Sp8 is crucial for limb outgrowth and neuropore closure. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12195-200