Lx Gene Detail

Summary

• Symbol
  Lx
• Name
  luxate

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96856
  NCBI Gene: 17034
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  7 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  21 phenotypes from 1 allele in 2 genetic backgrounds
  4 phenotypes from multigenic genotypes
  8 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Mutant homozygotes exhibit preaxial polydactyly or oligodactyly of the hindfeet, reductions in the tibia, femur and pubis, fewer sacral vertebrae, and defects of the urogenital system. Heterozygotes may have preaxial polydactyly of the hindfeet.

Sequences &
Gene Models

• NCBI Gene
  17034

Other
Accession IDs

MGD-MRK-11946

References

• Summaries
  All 15

  Phenotypes 8
• Earliest
  J:222 CARTER TC, Position of luxate in the third linkage group of the house mouse. Nature. 1949 Dec 31;164(4183):1138
• Latest
  J:81331 Yada Y, et al., The mouse polydactylous mutation, luxate (lx), causes anterior shift of the anteroposterior border in the developing hindlimb bud. Int J Dev Biol. 2002;46(7):975-82