Lyb7 Gene Detail

Summary

• Symbol
  Lyb7
• Name
  B-lymphocyte antigen 7
• Synonyms
  Lyb-7

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:96890
  NCBI Gene: 104177
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

This locus controls antigen present on a subset of mature B lymphocytes. Anti-Lyb7.1 blocks in vitro response to TNP-Ficoll and some TI-2 antigens. DBA/2 and C3H/He are susceptible to anti-Ly7.1 antibody block; C57BL/6 and AL/N are not susceptible. Heterozygotes are susceptible.

Sequences &
Gene Models

• NCBI Gene
  104177

Other
Accession IDs

MGD-MRK-12059, MGD-MRK-12065

References

• Summaries
  All 5
• Earliest
  J:6139 Subbarao B, et al., Lyb-7, a new B cell alloantigen controlled by genes linked to the IgCH locus. J Immunol. 1979 Jun;122(6):2279-85
• Latest
  J:6943 Subbarao B, et al., Lyb antigens and their role in B lymphocyte activation. Immunol Rev. 1982;69:81-97