Micrl QTL Detail

Summary

• Symbol
  Micrl
• Name
  microwave induced increase in complement receptor B cells

• Feature Type
  QTL
• IDs
  MGI:96981
  NCBI Gene: 110875

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  17 phenotype references
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  17 strains or lines available

This locus controls susceptibility to induced transitory increase in C3 receptor-bearing B lymphocytes when stimulated by microwave exposure. A dominant R (responder) allele and a recessive n (non-responder) allele have been identified.

Sequences &
Gene Models

• NCBI Gene
  110875

Other
Accession IDs

MGD-MRK-12231

References

• Summaries
  All 18

  Phenotypes 17
• Earliest
  J:6835 Schlagel CJ, et al., Evidence for genetic control of microwave-induced augmentation of complement receptor-bearing B lymphocytes. J Immunol. 1982 Oct;129(4):1530-3
• Latest
  J:357723 Sirbulescu RF, et al., Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis. FASEB J. 2024 Jul 15;38(13):e23796