Mod1r Gene Detail

Summary

• Symbol
  Mod1r
• Name
  malic enzyme, regulator

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97044
  NCBI Gene: 109664
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

Strain differences in hepatic (cytoxolic) malic enzyme activity are attributable to the Mod1r gene. Differences in biochemical indices and in activity of purified enzyme suggests differences in structure as well as in quantity of enzyme produced.

Sequences &
Gene Models

• NCBI Gene
  109664

Other
Accession IDs

MGD-MRK-12346

References

• Summaries
  All 3
• Earliest
  J:20246 Henderson NS, Isozymes and genetic control of NADP-malate dehydrogenase in mice. Arch Biochem Biophys. 1966 Oct;117(1):28-33
• Latest
  J:1881 Coleman DL, et al., Genetic regulation of malic enzyme activity in the mouse. J Biol Chem. 1991 Nov 15;266(32):21997-2002