Mp Gene Detail

Summary

• Symbol
  Mp
• Name
  micropinna microphthalmia

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97070
  NCBI Gene: 104327
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 18, Syntenic

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotypes from 1 allele in 2 genetic backgrounds
  3 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  1 strains or lines available

Homozygotes for a radiation-induced allele show reduced body weight, closed eyelids, microphthalmia, ciliary body malformation, severe ocular defects, small ears, hindlimb syndactyly and fused phalanges. Heterozygotes show reduced body weight, small earsand similar eye defects but no syndactyly.

Sequences &
Gene Models

• NCBI Gene
  104327

Other
Accession IDs

MGD-MRK-12399

References

• Summaries
  All 5

  Phenotypes 3
• Earliest
  J:11403 Hatta M, et al., Genomic organization and chromosomal mapping of the mouse P-cadherin gene. Nucleic Acids Res. 1991 Aug 25;19(16):4437-41
• Latest
  J:203031 Rainger J, et al., A Trans-Acting protein effect causes severe eye malformation in the Mp mouse. PLoS Genet. 2013;9(12):e1003998