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Myhc Complex/Cluster/Region Detail
Summary
  • Symbol
    Myhc
  • Name
    myosin heavy chain, cardiac muscle complex
  • Feature Type
    complex/cluster/region
  • IDs
    MGI:97254
    NCBI Gene: 111671
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 14, Syntenic
  • Mapping Data
    2 experiments
Mutations,
Alleles, and
Phenotypes
less
Homozygous mutations in this gene cause embryonic lethality around E11-12.5 due to cardiac defects. Heterozygous mice show cardiac function changes and cardiac myofiber pathological changes.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    5
  • Tissues
    2
  • Literature Summary
    28
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 2
    Primer pair 1
    Other 1
Other
Accession IDs
less
MGD-MRK-12740
References
more
  • Summaries
    All 61
    Developmental Gene Expression 28
  • Earliest
    J:7444 Czosnek H, et al., The genes coding for the muscle contractile proteins, myosin heavy chain, myosin light chain 2, and skeletal muscle actin are located on three different mouse chromosomes. EMBO J. 1982;1(11):1299-305
  • Latest
    J:342315 Rao J, et al., Reconstructing human brown fat developmental trajectory in vitro. Dev Cell. 2023 Nov 6;58(21):2359-2375.e8
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory