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Opcml Gene Detail
Summary
  • Symbol
    Opcml
  • Name
    opioid binding protein/cell adhesion molecule-like
  • Synonyms
    2900075O15Rik, B930023M13Rik, LOC235104, MGC:99974, Obcam
  • Feature Type
    protein coding gene
  • IDs
    MGI:97397
    NCBI Gene: 330908
  • Alliance
    gene page
  • Transcription Start Sites
    27 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:27702071-28836706 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 13.73 cM
  • Mapping Data
    14 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32180 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    4
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97397
 protein coding gene Chr9:27702050-28836706 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034510
 protein coding gene Chr9:25295684-26478781 (+)
A/J MGP_AJ_G0034488
 protein coding gene Chr9:24713869-25860421 (+)
AKR/J MGP_AKRJ_G0034414
 protein coding gene Chr9:25207795-26375775 (+)
BALB/cJ MGP_BALBcJ_G0034479
 protein coding gene Chr9:24620716-25766485 (+)
C3H/HeJ MGP_C3HHeJ_G0034191
 protein coding gene Chr9:25590490-26746683 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035000
 protein coding gene Chr9:26217574-27448814 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031930
 protein coding gene Chr9:23602053-24747244 (+)
CAST/EiJ MGP_CASTEiJ_G0033514
 protein coding gene Chr9:25394081-26588932 (+)
CBA/J MGP_CBAJ_G0034164
 protein coding gene Chr9:27155033-28348471 (+)
DBA/2J MGP_DBA2J_G0034322
 protein coding gene Chr9:24739410-25876207 (+)
FVB/NJ MGP_FVBNJ_G0034265
 protein coding gene Chr9:24159818-25306355 (+)
LP/J MGP_LPJ_G0034408
 protein coding gene Chr9:25483238-26653544 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034309
 protein coding gene Chr9:28831077-30045678 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035020
 protein coding gene Chr9:25213575-26390307 (+)
PWK/PhJ MGP_PWKPhJ_G0033219
 protein coding gene Chr9:24658412-25808431 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033053
 protein coding gene Chr9:25295275-26467912 (+)
WSB/EiJ MGP_WSBEiJ_G0033629
 protein coding gene Chr9:24957592-26134522 (+)



Homology
more
  • Human Ortholog
    OPCML, opioid binding protein/cell adhesion molecule like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OPCML, opioid binding protein/cell adhesion molecule like
  • Synonyms
    IGLON1, OBCAM, OPCM
  • Links
    NCBI Gene ID: 4978
    neXtProt AC: NX_Q14982
    UniProt: Q14982

  • Chr Location
    11q25; chr11:132414977-133532501 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human OPCML associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    12 phenotype references
Homozygous knockout has no cardiac effect.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

Cellular Component
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    955
  • Tissues
    82
  • cDNA Data
    12
  • Literature Summary
    10
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062257 Ensembl Gene Model | MGI Sequence Detail 1134636 C57BL/6J ±  kb
transcript ENSMUST00000073822 Ensembl | MGI Sequence Detail 2378 Not Applicable  
polypeptide ENSMUSP00000073493 Ensembl | MGI Sequence Detail 345 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Other 2

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-12968, MGI:1920295, MGI:2143136, MGI:2443164, MGI:2685027
References
more
  • Summaries
    All 47
    Developmental Gene Expression 10
    Phenotypes 12
  • Earliest
    J:4131 Chakraborti A, et al., Genetic mapping of opioid binding protein gene(s) to mouse chromosome 9. Mamm Genome. 1993;4(3):179-82
  • Latest
    J:354852 Singh K, et al., The IgLON family of cell adhesion molecules expressed in developing neural circuits ensure the proper functioning of the sensory system in mice. Sci Rep. 2024 Sep 30;14(1):22593
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory