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Oas1g Gene Detail
Summary
  • Symbol
    Oas1g
  • Name
    2'-5' oligoadenylate synthetase 1G
  • Synonyms
    L2, Mmu-L, Mmu-L2, Oas1a, Oias-1, Oias1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97429
    NCBI Gene: 23960
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:121014205-121025676 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 60.65 cM, cytoband F
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    490 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97429
 protein coding gene Chr5:121014205-121025676 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030019
 protein coding gene Chr5:124298288-124338462 (-)
A/J MGP_AJ_G0029984
 protein coding gene Chr5:119145067-119172523 (-)
AKR/J MGP_AKRJ_G0029922
 protein coding gene Chr5:123016432-123053391 (-)
BALB/cJ MGP_BALBcJ_G0029995
 protein coding gene Chr5:120605796-120619036 (-)
C3H/HeJ MGP_C3HHeJ_G0029714
 protein coding gene Chr5:123562327-123563609 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0027672
 protein coding gene Chr5:113839883-113846027 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0029683
 protein coding gene Chr5:134020998-134064149 (-)
DBA/2J MGP_DBA2J_G0029832
 protein coding gene Chr5:119286905-119294888 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0029920
 protein coding gene Chr5:124773146-124801535 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029819
 protein coding gene Chr5:137953022-138011456 (-)
NZO/HlLtJ no annotation
PWK/PhJ MGP_PWKPhJ_G0028835
 protein coding gene Chr5:118031405-118046191 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OAS1, 2'-5'-oligoadenylate synthetase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OAS1, 2'-5'-oligoadenylate synthetase 1
  • Synonyms
    E18/E16, IFI-4, IMD100, OIAS, OIASI
  • Links
    NCBI Gene ID: 4938
    neXtProt AC: NX_P00973
    UniProt: P00973

  • Chr Location
    12q24.13; chr12:112905856-112933219 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human OAS1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    42
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    802
  • Tissues
    17
  • cDNA Data
    30
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 23960 NCBI Gene Model | MGI Sequence Detail 11472 C57BL/6J ±  kb
    transcript NR_126529 RefSeq | MGI Sequence Detail 2069 ZRU/MplStud  
    polypeptide NP_035982 RefSeq | MGI Sequence Detail 367 ZRU/MplStud  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    Molecular
    Reagents
    less
    • All nucleic 37
      Genomic 4
      cDNA 31
      Primer pair 1
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGD-MRK-13023, MGD-MRK-13025, MGI:2140890
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 15
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory