Om Gene Detail

Summary

• Symbol
  Om
• Name
  ovum mutant

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97434
  NCBI Gene: 109599
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 11, Syntenic
• Mapping Data
  14 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  7 phenotypes from 1 allele in 1 genetic background
  17 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  2 strains or lines available

The DDK strain is homozygous for a spontaneous mutation resulting in high embryonic loss by the blastocyst stage when DDK ova are fertilized with sperm from normal strains. Lethality is apparently due to low intracellular pH and impaired gap junctions.

Sequences &
Gene Models

• NCBI Gene
  109599

Other
Accession IDs

MGD-MRK-13031

References

• Summaries
  All 28

  Phenotypes 17
• Earliest
  J:156917 Wakasugi N, et al., Differences of fertility in reciprocal crosses between inbred strains of mice. DDK, KK and NC. J Reprod Fertil. 1967 Feb;13(1):41-50
• Latest
  J:105162 Bell TA, et al., The Paternal Gene of the DDK Syndrome Maps to the Schlafen Gene Cluster on Mouse Chromosome 11. Genetics. 2006 Jan;172(1):411-23