Os Gene Detail

Summary

• Symbol
  Os
• Name
  oligosyndactylism
• Synonyms
  94-A, 94-K, PlmTgN(Pgk1)1Ddp, PlmTgN(Pgk1)2Ddp

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:97446
  NCBI Gene: 109678
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 8, Syntenic
• Mapping Data
  39 experiments

Strain
Comparison

• RFLP
  2

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  34 phenotypes from 1 allele in 4 genetic backgrounds
  1 images
  33 phenotype references
  

• All Mutations and Alleles
  3
• Radiation induced
  1
• Transgenic
  2
• Find Mice (IMSR)
  9 strains or lines available

Mutations in this gene result in heterozygous mice with limb and kidney abnormalities. The homozygote dies soon after implantation.

Expression

• cDNA Data
  1

Sequences &
Gene Models

• NCBI Gene
  109678

Molecular
Reagents

• All nucleic 10

  Genomic 9

  cDNA 1

Other
Accession IDs

MGD-MRK-13054, MGI:892015, MGI:892016

References

• Summaries
  All 62

  Phenotypes 33
• Earliest
  J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
• Latest
  J:348117 Okuma H, et al., N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on alpha-dystroglycan and prevents muscular dystrophy. Elife. 2023 Feb 1;12