Pcts QTL Detail

Summary

• Symbol
  Pcts
• Name
  plasmacytoma susceptibility

• Feature Type
  QTL
• IDs
  MGI:97519
  NCBI Gene: 107467

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 4, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  1 strains or lines available

This QTL, among others, influences susceptibility to plasmacytoma induced by plastics, paraffin oils, or pristine. BALB/cAn and NZB/BlNJ are genetically susceptible and DBA/2N mice are resistant.

Sequences &
Gene Models

• NCBI Gene
  107467

Other
Accession IDs

MGD-MRK-13199

References

• Summaries
  All 4

  Phenotypes 1
• Earliest
  J:15235 Mock BA, et al., Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9499-503
• Latest
  J:124158 Jawad M, et al., Target cell frequency is a genetically determined risk factor in radiation leukaemogenesis. Br J Radiol. 2007 Sep;80 Spec No 1:S56-62