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Pgm2 Gene Detail
Summary
  • Symbol
    Pgm2
  • Name
    phosphoglucomutase 2
  • Synonyms
    3230402E02Rik, Pgm-1, Pgm1
  • Feature Type
    protein coding gene
  • IDs
    MGI:97564
    NCBI Gene: 66681
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:64250293-64285694 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 32.80 cM, cytoband C3.3
  • Mapping Data
    84 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1030 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97564
 protein coding gene Chr5:64250258-64285698 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029565
 protein coding gene Chr5:63660433-63699457 (+)
A/J MGP_AJ_G0029533
 protein coding gene Chr5:61295035-61327194 (+)
AKR/J MGP_AKRJ_G0029481
 protein coding gene Chr5:63210868-63243346 (+)
BALB/cJ MGP_BALBcJ_G0029542
 protein coding gene Chr5:61974047-62003363 (+)
C3H/HeJ MGP_C3HHeJ_G0029265
 protein coding gene Chr5:63580325-63610948 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029996
 protein coding gene Chr5:66305526-66341363 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027236
 protein coding gene Chr5:57396250-57425774 (+)
CAST/EiJ MGP_CASTEiJ_G0028673
 protein coding gene Chr5:62641706-62678874 (+)
CBA/J MGP_CBAJ_G0029234
 protein coding gene Chr5:68413981-68462315 (+)
DBA/2J MGP_DBA2J_G0029380
 protein coding gene Chr5:61324305-61356934 (+)
FVB/NJ MGP_FVBNJ_G0029340
 protein coding gene Chr5:60501636-60531418 (+)
LP/J MGP_LPJ_G0029465
 protein coding gene Chr5:64127974-64161866 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029368
 protein coding gene Chr5:71357745-71393317 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030029
 protein coding gene Chr5:62903317-62934323 (+)
PWK/PhJ MGP_PWKPhJ_G0028397
 protein coding gene Chr5:60295178-60325020 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028231
 protein coding gene Chr5:62248325-62280187 (+)
WSB/EiJ MGP_WSBEiJ_G0028754
 protein coding gene Chr5:63121264-63153190 (+)



Homology
more
  • Human Ortholog
    PGM2, phosphoglucomutase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PGM2, phosphoglucomutase 2
  • Synonyms
    MSTP006
  • Links
    NCBI Gene ID: 55276
    neXtProt AC: NX_Q96G03
    UniProt: Q96G03

  • Chr Location
    4p14; chr4:37826660-37862937 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 6 alleles in 3 genetic backgrounds
    26 phenotype references
  • All Mutations and Alleles
    16
  • Chemically induced (ENU)
    4
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    3
  • Gene trapped
    2
  • Radiation induced
    1
  • Spontaneous
    2
  • Targeted
    1
  • Genomic Mutations
    4 involving Pgm2
  • Incidental Mutations
    Mutagenetix , APF , CvDC
  • Find Mice (IMSR)
    46 strains or lines available
Four electrophoretic variants are known, each with a 5-band pattern: the a allele in C57BL/6, BALB/c and AKR; b allele in DBA/2 and SJL; c allele in C3H/He; and d allele in 129/Re. Heterozygotes show a mixture of bands. Mice homozygous for a spontaneous null allele or ENU induced alleles are viable.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    902
  • Tissues
    99
  • cDNA Data
    46
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029171 Ensembl Gene Model | MGI Sequence Detail 35402 C57BL/6J ±  kb
transcript ENSMUST00000087324 Ensembl | MGI Sequence Detail 2369 Not Applicable  
polypeptide ENSMUSP00000084582 Ensembl | MGI Sequence Detail 620 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000012615 phosphopentomutase
    (term hierarchy)
  • EC
    5.4.2.2, 5.4.2.7
  • InterPro Domains
    IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
    IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
    IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III
    IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III
    IPR016066 Alpha-D-phosphohexomutase, conserved site
    IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily
Molecular
Reagents
less
  • All nucleic 49
    cDNA 46
    Primer pair 3

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13275, MGD-MRK-13278, MGI:1913931, MGI:6194612
References
more
  • Summaries
    All 128
    Developmental Gene Expression 6
    Gene Ontology 12
    Phenotypes 26
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:296367 Roberts GAG, et al., Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory