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Prl3d1 Gene Detail
Summary
  • Symbol
    Prl3d1
  • Name
    prolactin family 3, subfamily d, member 1
  • Synonyms
    Csh1, mPL-I, Pl-1, Pl1, placental lactogen 1, PL-Ia, prolactin-like 2
  • Feature Type
    protein coding gene
  • IDs
    MGI:97606
    NCBI Gene: 18775
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27278173-27284241 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.27 cM
  • Mapping Data
    13 experiments
Strain
Comparison
more
  • SNPs within 2kb
    338 from dbSNP Build 142
  • Strain Annotations
    15
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97606
 protein coding gene Chr13:27278172-27284243 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020391
 protein coding gene Chr13:24739811-24774230 (+)
A/J MGP_AJ_G0020341
 protein coding gene Chr13:24186518-24190703 (+)
AKR/J MGP_AKRJ_G0020320
 protein coding gene Chr13:24458612-24467490 (+)
BALB/cJ MGP_BALBcJ_G0020338
 protein coding gene Chr13:24154454-24172322 (+)
C3H/HeJ MGP_C3HHeJ_G0020143
 protein coding gene Chr13:24539444-24588434 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020775
 protein coding gene Chr13:25558746-25567508 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0019659
 protein coding gene Chr13:24286656-24323485 (+)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ MGP_FVBNJ_G0020207
 protein coding gene Chr13:23317514-23344434 (+)
LP/J MGP_LPJ_G0020297
 protein coding gene Chr13:24962754-25009971 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020233
 protein coding gene Chr13:26874385-26885256 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020817
 protein coding gene Chr13:24358320-24432154 (+)
PWK/PhJ MGP_PWKPhJ_G0019413
 protein coding gene Chr13:23690578-23697144 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019229
 protein coding gene Chr13:23215847-23221830 (+)
WSB/EiJ MGP_WSBEiJ_G0019721
 protein coding gene Chr13:24521002-24526846 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Prl3d1
  • Incidental Mutations
    Mutagenetix
  • Find Mice (IMSR)
    16 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    909
  • Tissues
    51
  • cDNA Data
    13
  • Literature Summary
    152
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057170 Ensembl Gene Model | MGI Sequence Detail 6069 C57BL/6J ±  kb
transcript ENSMUST00000225330 Ensembl | MGI Sequence Detail 866 Not Applicable  
polypeptide ENSMUSP00000152890 Ensembl | MGI Sequence Detail 224 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 17
    Primer pair 9
    Other 15

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-13339, MGD-MRK-13341, MGI:2145212
References
more
  • Summaries
    All 209
    Developmental Gene Expression 152
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:348843 Yang N, et al., Trophoblastic signals facilitate endometrial interferon response and lipid metabolism, ensuring normal decidualization. Cell Rep. 2024 May 18;43(6):114246
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory