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Prl3b1 Gene Detail
Summary
  • Symbol
    Prl3b1
  • Name
    prolactin family 3, subfamily b, member 1
  • Synonyms
    Csh2, mplII, mPL-II, PL, Pl-2, Pl2, prolactin-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:97607
    NCBI Gene: 18776
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:27426413-27433666 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 12.35 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    400 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97607
 protein coding gene Chr13:27425830-27433666 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020393
 protein coding gene Chr13:24861142-24868359 (+)
A/J MGP_AJ_G0020344
 protein coding gene Chr13:24330476-24337729 (+)
AKR/J MGP_AKRJ_G0020324
 protein coding gene Chr13:24668963-24677391 (+)
BALB/cJ MGP_BALBcJ_G0020342
 protein coding gene Chr13:24331643-24340688 (+)
C3H/HeJ MGP_C3HHeJ_G0020145
 protein coding gene Chr13:24732146-24739399 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020779
 protein coding gene Chr13:25727247-25734321 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018364
 protein coding gene Chr13:22962482-22970287 (+)
CAST/EiJ MGP_CASTEiJ_G0019663
 protein coding gene Chr13:24422732-24431557 (+)
CBA/J MGP_CBAJ_G0020099
 protein coding gene Chr13:26796913-26805648 (+)
DBA/2J MGP_DBA2J_G0020223
 protein coding gene Chr13:23860668-23867923 (+)
FVB/NJ MGP_FVBNJ_G0020209
 protein coding gene Chr13:23471545-23478786 (+)
LP/J MGP_LPJ_G0020299
 protein coding gene Chr13:25127204-25136492 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020237
 protein coding gene Chr13:27048475-27061030 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020819
 protein coding gene Chr13:24515816-24523065 (+)
PWK/PhJ MGP_PWKPhJ_G0019417
 protein coding gene Chr13:23772794-23780301 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019233
 protein coding gene Chr13:23422118-23430316 (+)
WSB/EiJ MGP_WSBEiJ_G0019723
 protein coding gene Chr13:24686311-24694133 (+)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    789
  • Tissues
    37
  • cDNA Data
    228
  • Literature Summary
    55
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 18776 NCBI Gene Model | MGI Sequence Detail 7254 C57BL/6J ±  kb
transcript NM_008865 RefSeq | MGI Sequence Detail 879 ZRU/MplStud  
polypeptide P09586 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 241
    Genomic 2
    cDNA 232
    Primer pair 3
    Other 4

    Microarray probesets 4
Other
Accession IDs
less
MGD-MRK-13340, MGD-MRK-13342
References
more
  • Summaries
    All 103
    Developmental Gene Expression 55
    Gene Ontology 5
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345473 Lee JG, et al., PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development. Nat Commun. 2024 Feb 19;15(1):1487
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory