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ple Gene Detail
Summary
  • Symbol
    ple
  • Name
    perinatal lethality
  • Synonyms
    Tg.ple
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:97617
    NCBI Gene: 18809
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome 15, cytoband F
  • Mapping Data
    9 experiments
Strain
Comparison
more
  • RFLP
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutations in this gene result in perinatal death of homozygous mice.
Expression
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  • cDNA Data
Sequences &
Gene Models
less
Molecular
Reagents
less
  • All nucleic 5
    Genomic 3
    cDNA 1
    Other 1
Other
Accession IDs
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MGD-MRK-13357, MGD-MRK-15076
References
more
  • Summaries
    All 5
    Phenotypes 2
  • Earliest
    J:9878 Beier DR, et al., Perinatal lethality (ple): a mutation caused by integration of a transgene into distal mouse chromosome 15. Genomics. 1989 May;4(4):498-504
  • Latest
    J:79600 Sun Y, et al., Magnetic resonance imaging assessment of a murine model of recessive polycystic kidney disease. Comp Med. 2002 Oct;52(5):433-8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory