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Is(In8B2-8B3.1;6C1)1Tshir Cytogenetic Marker Detail
Summary
  • Symbol
    Is(In8B2-8B3.1;6C1)1Tshir
  • Name
    Insertion, Chr8 B2-B3.1 into Chr 6C1, Toshihiko Shiroishi 1
  • Synonyms
    Rim4
  • Feature Type
    insertion
  • IDs
    MGI:97926
    NCBI Gene: 110241
Location &
Maps
more
  • Sequence Map
    Chr6:68125501-74184556 bp
    From MGI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, Syntenic
  • Mapping Data
    5 experiments
Human Diseases
more
  • Diseases
    1 with Is(In8B2-8B3.1;6C1)1Tshir mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    29 phenotypes from 1 allele in 1 genetic background
    6 phenotypes from multigenic genotypes
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
MHC recombinants between wild-derived H2 and laboratory chromosomes show high rates of mutation that may be unlinked to MHC, but appear to be induced by the intra-MHC recombination.
Sequences &
Gene Models
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Other
Accession IDs
less
MGD-MRK-13891
References
more
  • Summaries
    All 7
    Diseases 1
    Phenotypes 4
  • Earliest
    J:3639 Shiroishi T, et al., III. Mammalian genetics. Mouse visible mutations of the intra-MHC recombinants. Annu Rep Natl Inst Genet Jpn. 1992;42:49
  • Latest
    J:198239 Tamura M, et al., Overdosage of Hand2 causes limb and heart defects in the human chromosomal disorder partial trisomy distal 4q. Hum Mol Genet. 2013 Jun 15;22(12):2471-81
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory