Rmcf Gene Detail

Summary

• Symbol
  Rmcf
• Name
  resistance to MCF virus

• Feature Type
  unclassified gene
• IDs
  MGI:97933
  NCBI Gene: 109928
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, Syntenic
• Mapping Data
  17 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 2 alleles in 6 genetic backgrounds
  9 phenotype references
  

• All Mutations and Alleles
  2
• Spontaneous
  2
• Find Mice (IMSR)
  23 strains or lines available

This locus controls resistance of cells to infection by mink cell focus-forming murine leukemia viruses. The dominant r (resistance) allele is found in strains DBA/1, DBA/2 and CBA/Ca; the recessive s (susceptible) allele is found in AKR/J, C57BL/6, BALB/c, CBA/J, NFS, NZB and 129/J.

Sequences &
Gene Models

• All Sequences
  2

• NCBI Gene
  109928

Other
Accession IDs

MGD-MRK-13900

References

• Summaries
  All 15

  Phenotypes 9
• Earliest
  J:7108 Hartley JW, et al., A mouse gene on chromosome 5 that restricts infectivity of mink cell focus-forming recombinant murine leukemia viruses. J Exp Med. 1983 Jul 1;158(1):16-24
• Latest
  J:354914 Brockett AT, et al., Psilocybin decreases neural responsiveness and increases functional connectivity while preserving pure-tone frequency selectivity in mouse auditory cortex. J Neurophysiol. 2024 Jul 1;132(1):45-53