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Rn4.5s Gene Detail
Summary
  • Symbol
    Rn4.5s
  • Name
    4.5S RNA
  • Feature Type
    rRNA gene
  • IDs
    MGI:97946
    NCBI Gene: 19799
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr6:47631855-47632028 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 22.94 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5 from dbSNP Build 142
  • Strain Annotations
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_97946
 rRNA gene Chr6:47631855-47632028 (-)
129S1/SvImJ no annotation
A/J no annotation
AKR/J no annotation
BALB/cJ no annotation
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit abnormal embryogenesis at E6.5 and die prior to E9.5.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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  • Assay Results
    2
  • Tissues
    1
  • cDNA Data
    1
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Other Mouse Links
      GEO
    Sequences &
    Gene Models
    less
    • All Sequences
      6
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 19799 NCBI Gene Model | MGI Sequence Detail 174 C57BL/6J ±  kb
    transcript NR_002841 RefSeq | MGI Sequence Detail 174 ZRU/MplStud  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      Genomic 3
      cDNA 1
      Other 1
    Other
    Accession IDs
    less
    MGD-MRK-13922
    References
    more
    • Summaries
      All 14
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 1
    • Earliest
      J:32375 Schoeniger LO, et al., 4.5S RNA is encoded by hundreds of tandemly linked genes, has a short half-life, and is hydrogen bonded in vivo to poly(A)-terminated RNAs in the cytoplasm of cultured mouse cells. Mol Cell Biol. 1986 May;6(5):1508-19
    • Latest
      J:344073 Yoshimoto R, et al., 4.5SH RNA counteracts deleterious exonization of SINE B1 in mice. Mol Cell. 2023 Dec 21;83(24):4479-4493.e6
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory