Rv2 QTL Detail

Summary

• Symbol
  Rv2
• Name
  Rauscher leukemia virus susceptibility 2
• Synonyms
  Rv-2

• Feature Type
  QTL
• IDs
  MGI:98210
  NCBI Gene: 107725

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 9, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  1 experiment

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 2 genetic backgrounds
  1 phenotype reference
  

• All Mutations and Alleles
  3
• QTL
  3
• Find Mice (IMSR)
  0 strains or lines available

This locus affects susceptibility to the spleen focus-forming component of Rauscher leukemia virus. The dominant resistance allele is found in C57BL/6 and C57BL/10 strains; the recessive susceptibility allele in BALB/c and CBA/Lac. Rv2 may be identical to Mst1r.

Sequences &
Gene Models

• NCBI Gene
  107725

Other
Accession IDs

MGD-MRK-14256, MGD-MRK-14259

References

• Summaries
  All 4

  Phenotypes 1
• Earliest
  J:5425 Toth FD, et al., Inheritance of susceptibility and resistance to Rauscher leukaemia virus. Acta Microbiol Acad Sci Hung. 1973;20(3):183-9
• Latest
  J:7613 Heller E, et al., Chromosomal assignment of two murine genes controlling susceptibility to spleen focus formation by Rauscher leukemia virus. Exp Hematol. 1984 Sep;12(8):645-9