Scom QTL Detail

Summary

• Symbol
  Scom
• Name
  scopolamine modification of exploratory activity

• Feature Type
  QTL
• IDs
  MGI:98253
  NCBI Gene: 110799

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 17, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

This QTL modulates the effect of scopolamine in reducing activity level of mice with high basal short-term exploratory activity and increasing that of mice with low basal activity. Absence of dose-related activity change is seen in BALB/cBy and presence of the activity change in C57BL/6By.

Sequences &
Gene Models

• NCBI Gene
  110799

Other
Accession IDs

MGD-MRK-14326

References

• Summaries
  All 3

  Phenotypes 1
• Earliest
  J:5355 Oliverio A, et al., Exploratory activity: genetic analysis of its modification by scopolamine and amphetamine. Physiol Behav. 1973 May;10(5):893-9
• Latest
  J:6936 Walker MC, et al., Genetic control of corticosteroid side-chain isomerase activity in the mouse. Endocrinology. 1983 Mar;112(3):924-30