Sig Gene Detail

Summary

• Symbol
  Sig
• Name
  sightless

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98305
  NCBI Gene: 109565
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Chr6:4464884-8778488 bp

  From MGI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 6, Syntenic
• Mapping Data
  10 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  16 phenotypes from 1 allele in 2 genetic backgrounds
  3 phenotype references
  

• All Mutations and Alleles
  1
• Radiation induced
  1
• Find Mice (IMSR)
  1 strains or lines available

Mutations in this gene result in hydrocephaly, open eye lids at birth and sometimes foot anomalies. The homozygous condition is lethal.

Sequences &
Gene Models

• NCBI Gene
  109565

Other
Accession IDs

MGD-MRK-14412

References

• Summaries
  All 16

  Phenotypes 3
• Earliest
  J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
• Latest
  J:32894 Primo-Parmo SL, et al., The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics. 1996 May 1;33(3):498-507