stu Gene Detail

Summary

• Symbol
  stu
• Name
  stumbler

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98439
  NCBI Gene: 20906
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 2, Syntenic
• Mapping Data
  2 experiments

Strain
Comparison

• PCR
  1

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  21 phenotypes from 1 allele in 2 genetic backgrounds
  4 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Mutations in this gene result at first in an abnormal gait. Progressive loss of Purkinje cells results in early death.

Sequences &
Gene Models

• NCBI Gene
  20906

Molecular
Reagents

• All nucleic 1

  Primer pair 1

Other
Accession IDs

MGD-MRK-14638

References

• Summaries
  All 5

  Phenotypes 4
• Earliest
  J:6464 Caddy KW, et al., Stumbler, a new mutant mouse with cerebellar disease. Brain Res. 1981 Mar 9;208(1):251-5
• Latest
  J:21507 Frankel WN, et al., The stumbler mutation maps to proximal mouse Chromosome 2. Mamm Genome. 1994 Nov;5(11):659-662