Surf2 Gene Detail

Summary

• Symbol
  Surf2
• Name
  surfeit gene 2
• Synonyms
  Surf-2

• Feature Type
  protein coding gene
• IDs
  MGI:98444
  NCBI Gene: 20931
• Member of
  Surf cluster
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr2:26806420-26810199 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 2, 19.10 cM
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  156 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_98444	protein coding gene	Chr2:26806379-26810199 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025501	protein coding gene	Chr2:24888010-24891826 (+)
A/J	MGP_AJ_G0025478	protein coding gene	Chr2:23943899-23947715 (+)
AKR/J	MGP_AKRJ_G0025448	protein coding gene	Chr2:24724449-24728265 (+)
BALB/cJ	MGP_BALBcJ_G0025474	protein coding gene	Chr2:24061990-24065806 (+)
C3H/HeJ	MGP_C3HHeJ_G0025235	protein coding gene	Chr2:24663214-24667030 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025918	protein coding gene	Chr2:25730053-25733869 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0023329	protein coding gene	Chr2:22782739-22786602 (+)
CAST/EiJ	MGP_CASTEiJ_G0024698	protein coding gene	Chr2:24540316-24544140 (+)
CBA/J	MGP_CBAJ_G0025213	protein coding gene	Chr2:26621723-26625539 (+)
DBA/2J	MGP_DBA2J_G0025346	protein coding gene	Chr2:23760402-23764218 (+)
FVB/NJ	MGP_FVBNJ_G0025308	protein coding gene	Chr2:23515618-23519434 (+)
LP/J	MGP_LPJ_G0025432	protein coding gene	Chr2:24833655-24837471 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0025339	protein coding gene	Chr2:26680721-26684537 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025977	protein coding gene	Chr2:24665811-24669627 (+)
PWK/PhJ	MGP_PWKPhJ_G0024446	protein coding gene	Chr2:23554471-23558300 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0024246	protein coding gene	Chr2:24818189-24822004 (+)
WSB/EiJ	MGP_WSBEiJ_G0024767	protein coding gene	Chr2:24783532-24787348 (+)

Homology

• Human Ortholog
  SURF2, surfeit 2

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  SURF2, surfeit 2
  
• Synonyms
  SURF-2
• Links
  HGNC:11475

  NCBI Gene ID: 6835

  neXtProt AC: NX_Q15527

  UniProt: Q15527

  
  
• Chr Location
  9q34.2; chr9:133356550-133361158 (+)  GRCh38

---

• MGI Vertebrate Homology
  Surf2 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: SURF2
• Gene Tree
  Surf2
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  5 phenotype references
  

• All Mutations and Alleles
  6
• Endonuclease-mediated
  1
• Gene trapped
  4
• Targeted
  1
• Find Mice (IMSR)
  9 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  7
• GO References
  2

Expression

• Assay Results
  711
• Tissues
  1
• cDNA Data
  10
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase surf2

Sequences &
Gene Models

• All Sequences
  65
• RefSeq
  17
• UniProt
  4
• CCDS
  CCDS15816.1

• Ensembl
  ENSMUSG00000014873 (Evidence)
• NCBI Gene
  20931

Representative Sequences			Length	Strain/Species
genomic	20931	NCBI Gene Model | MGI Sequence Detail	3780	C57BL/6J
transcript	NR_185253	RefSeq | MGI Sequence Detail	1298	ZRU/MplStud
polypeptide	P09926	UniProt | EBI | MGI Sequence Detail	257	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000015841 surfeit locus protein 2
  (term hierarchy)
• InterPro Domains
  IPR008833 Surfeit locus protein 2

Molecular
Reagents

• All nucleic 20

  Genomic 2

  cDNA 17

  Primer pair 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGD-MRK-14645, MGD-MRK-14652

References

• Summaries
  All 34

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 5
• Earliest
  J:29566 Williams TJ, et al., The MES-1 murine enhancer element is closely associated with the heterogeneous 5' ends of two divergent transcription units. Mol Cell Biol. 1986 Dec;6(12):4558-69
• Latest
  J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Surf2:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr16826	Chr2:26806372-26806408 (+)	-30 bp
Tssr16827	Chr2:26806412-26806433 (+)	3 bp
Tssr16828	Chr2:26806799-26806847 (+)	403 bp