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Surf6 Gene Detail
Summary
  • Symbol
    Surf6
  • Name
    surfeit gene 6
  • Synonyms
    D2Wsu129e, Surf-6
  • Feature Type
    protein coding gene
  • IDs
    MGI:98447
    NCBI Gene: 20935
  • Member of
    Surf cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:26780430-26792899 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.08 cM
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    384 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98447
 protein coding gene Chr2:26778640-26792899 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025497
 protein coding gene Chr2:24860379-24874522 (-)
A/J MGP_AJ_G0025474
 protein coding gene Chr2:23916262-23930409 (-)
AKR/J MGP_AKRJ_G0025444
 protein coding gene Chr2:24692997-24709558 (-)
BALB/cJ MGP_BALBcJ_G0025470
 protein coding gene Chr2:24031722-24046269 (-)
C3H/HeJ MGP_C3HHeJ_G0025231
 protein coding gene Chr2:24634095-24648797 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025914
 protein coding gene Chr2:25691646-25707635 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023325
 protein coding gene Chr2:22754361-22768742 (-)
CAST/EiJ MGP_CASTEiJ_G0024694
 protein coding gene Chr2:24510006-24526801 (-)
CBA/J MGP_CBAJ_G0025209
 protein coding gene Chr2:26574577-26603262 (-)
DBA/2J MGP_DBA2J_G0025342
 protein coding gene Chr2:23729500-23744404 (-)
FVB/NJ MGP_FVBNJ_G0025304
 protein coding gene Chr2:23484548-23501611 (-)
LP/J MGP_LPJ_G0025428
 protein coding gene Chr2:24800322-24818678 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025335
 protein coding gene Chr2:26652130-26667230 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025973
 protein coding gene Chr2:24636341-24652325 (-)
PWK/PhJ MGP_PWKPhJ_G0024442
 protein coding gene Chr2:23524779-23539699 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024242
 protein coding gene Chr2:24783478-24804494 (-)
WSB/EiJ MGP_WSBEiJ_G0024763
 protein coding gene Chr2:24754547-24769698 (-)



Homology
more
  • Human Ortholog
    SURF6, surfeit 6
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SURF6, surfeit 6
  • Synonyms
    RRP14
  • Links
    NCBI Gene ID: 6838
    neXtProt AC: NX_O75683
    UniProt: O75683

  • Chr Location
    9q34.2; chr9:133328776-133336188 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    745
  • Tissues
    16
  • cDNA Data
    7
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 20935 NCBI Gene Model | MGI Sequence Detail 12470 C57BL/6J ±  kb
transcript NM_009298 RefSeq | MGI Sequence Detail 2996 ZRU/MplStud  
polypeptide P70279 UniProt | EBI | MGI Sequence Detail 355 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015843 surfeit locus protein 6
    (term hierarchy)
  • InterPro Domains
    IPR029190 Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain
    IPR007019 Surfeit locus 6
  • GlyGen
    P70279 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 16
    Genomic 2
    cDNA 10
    Primer pair 3
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14650, MGD-MRK-14655, MGD-MRK-35818, MGI:107352
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 4
  • Earliest
    J:10274 Huxley C, et al., The mouse surfeit locus contains a cluster of six genes associated with four CpG-rich islands in 32 kilobases of genomic DNA. Mol Cell Biol. 1990 Feb;10(2):605-14
  • Latest
    J:114487 Romanova LG, et al., Implication of Nucleolar Protein SURF6 in Ribosome Biogenesis and Preimplantation Mouse Development. Biol Reprod. 2006 Nov;75(5):690-6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory