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Tfcp2 Gene Detail
Summary
  • Symbol
    Tfcp2
  • Name
    transcription factor CP2
  • Synonyms
    CP-2, CP2, D230015P20Rik, LBP1, LBP-1c, LBP-1d, LSF, Tcfcp2, UBP-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98509
    NCBI Gene: 21422
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:100395893-100449889 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 56.33 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1111 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98509
 protein coding gene Chr15:100395083-100449896 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022354
 protein coding gene Chr15:102467804-102524033 (-)
A/J MGP_AJ_G0022316
 protein coding gene Chr15:98427838-98494107 (-)
AKR/J MGP_AKRJ_G0022292
 protein coding gene Chr15:101441092-101502492 (-)
BALB/cJ MGP_BALBcJ_G0022320
 protein coding gene Chr15:98548653-98604887 (-)
C3H/HeJ MGP_C3HHeJ_G0022090
 protein coding gene Chr15:101525472-101584873 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022768
 protein coding gene Chr15:106325978-106378047 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020293
 protein coding gene Chr15:94200447-94249026 (-)
CAST/EiJ MGP_CASTEiJ_G0021615
 protein coding gene Chr15:102380157-102435213 (-)
CBA/J MGP_CBAJ_G0022059
 protein coding gene Chr15:109959839-110008192 (-)
DBA/2J MGP_DBA2J_G0022186
 protein coding gene Chr15:97796330-97845372 (-)
FVB/NJ MGP_FVBNJ_G0022165
 protein coding gene Chr15:96808522-96862394 (-)
LP/J MGP_LPJ_G0022257
 protein coding gene Chr15:102637587-102687900 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022186
 protein coding gene Chr15:113678137-113744423 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022782
 protein coding gene Chr15:101446727-101498072 (-)
PWK/PhJ MGP_PWKPhJ_G0021354
 protein coding gene Chr15:97924682-97974374 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021186
 protein coding gene Chr15:101343405-101397943 (-)
WSB/EiJ MGP_WSBEiJ_G0021665
 protein coding gene Chr15:102074414-102122415 (-)



Homology
more
  • Human Ortholog
    TFCP2, transcription factor CP2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TFCP2, transcription factor CP2
  • Synonyms
    LBP1C, LSF, LSF1D, SEF, TFCP2C
  • Links
    NCBI Gene ID: 7024
    neXtProt AC: NX_Q12800
    UniProt: Q12800

  • Chr Location
    12q13.12-q13.13; chr12:51093656-51173135 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    27 phenotype references
Mice homozygous for a knock-out allele are viable, fertile and overtly normal with no apparent alterations in overall behavior, hematopoiesis, globin chain synthesis, or immunological function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    883
  • Tissues
    81
  • cDNA Data
    31
  • Literature Summary
    8
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000009733 Ensembl Gene Model | MGI Sequence Detail 53997 C57BL/6J ±  kb
transcript ENSMUST00000229581 Ensembl | MGI Sequence Detail 1903 Not Applicable  
polypeptide ENSMUSP00000155581 Ensembl | MGI Sequence Detail 505 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    Genomic 6
    cDNA 31
    Primer pair 2
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14761, MGI:2442498
References
more
  • Summaries
    All 66
    Developmental Gene Expression 8
    Diseases 1
    Gene Ontology 5
    Phenotypes 27
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:285676 Suzuki A, et al., Genes and microRNAs associated with mouse cleft palate: A systematic review and bioinformatics analysis. Mech Dev. 2018 Apr;150:21-27
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory