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Tcp11 Gene Detail
Summary
  • Symbol
    Tcp11
  • Name
    t-complex protein 11
  • Synonyms
    D17Ken1, Tcp-11
  • Feature Type
    protein coding gene
  • IDs
    MGI:98544
    NCBI Gene: 21463
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:28285725-28299583 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 14.62 cM, cytoband A3-B
  • Mapping Data
    5 experiments
Strain
Comparison
more
  • SNPs within 2kb
    95 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98544
 protein coding gene Chr17:28285719-28299613 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023432
 protein coding gene Chr17:27414129-27430610 (-)
A/J MGP_AJ_G0023390
 protein coding gene Chr17:26546530-26560213 (-)
AKR/J MGP_AKRJ_G0023355
 protein coding gene Chr17:26715660-26729435 (-)
BALB/cJ MGP_BALBcJ_G0023395
 protein coding gene Chr17:26807777-26821953 (-)
C3H/HeJ MGP_C3HHeJ_G0023156
 protein coding gene Chr17:27095939-27115732 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023837
 protein coding gene Chr17:28538748-28555592 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021312
 protein coding gene Chr17:23917907-23930581 (-)
CAST/EiJ MGP_CASTEiJ_G0022657
 protein coding gene Chr17:27074784-27088494 (-)
CBA/J MGP_CBAJ_G0023130
 protein coding gene Chr17:29539592-29554680 (-)
DBA/2J MGP_DBA2J_G0023261
 protein coding gene Chr17:26095716-26110287 (-)
FVB/NJ MGP_FVBNJ_G0023231
 protein coding gene Chr17:25890166-25904786 (-)
LP/J MGP_LPJ_G0023339
 protein coding gene Chr17:27677423-27691620 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023249
 protein coding gene Chr17:28996807-29019023 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023879
 protein coding gene Chr17:27136687-27152134 (-)
PWK/PhJ MGP_PWKPhJ_G0022407
 protein coding gene Chr17:24898080-24914141 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022225
 protein coding gene Chr17:25147490-25161687 (-)
WSB/EiJ MGP_WSBEiJ_G0022719
 protein coding gene Chr17:27130745-27145979 (-)



Homology
more
  • Human Ortholog
    TCP11, t-complex 11
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCP11, t-complex 11
  • Synonyms
    D6S230E, FPPR
  • Links
    NCBI Gene ID: 6954
    neXtProt AC: NX_Q8WWU5
    UniProt: Q8WWU5

  • Chr Location
    6p21.31; chr6:35118071-35148610 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    717
  • Tissues
    11
  • cDNA Data
    59
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21463 NCBI Gene Model | MGI Sequence Detail 13859 C57BL/6J ±  kb
transcript NM_001399994 RefSeq | MGI Sequence Detail 2058 ZRU/MplStud  
polypeptide Q01755 UniProt | EBI | MGI Sequence Detail 566 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 59
    cDNA 59

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-14816, MGD-MRK-14835, MGD-MRK-4493
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:11436 Mazarakis ND, et al., Isolation and characterisation of a testis-expressed developmentally regulated gene from the distal inversion of the mouse t-complex. Development. 1991 Feb;111(2):561-71
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory