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Trbv3 Gene Detail
Summary
  • Symbol
    Trbv3
  • Name
    T cell receptor beta, variable 3
  • Synonyms
    Gm2426
  • Feature Type
    gene segment
  • IDs
    MGI:98590
    NCBI Gene: 100039790
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:41025328-41025758 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 6, 19.12 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    143 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98590
gene segment Chr6:41025224-41025762 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002578
gene segment Chr6:39522639-39523177 (+)
A/J MGP_AJ_G0002549
gene segment Chr6:37802188-37802726 (+)
AKR/J MGP_AKRJ_G0002540
gene segment Chr6:39003576-39004114 (+)
BALB/cJ MGP_BALBcJ_G0002535
gene segment Chr6:38014726-38015264 (+)
C3H/HeJ MGP_C3HHeJ_G0002502
gene segment Chr6:39027281-39027819 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002676
gene segment Chr6:40516156-40516694 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002245
gene segment Chr6:35588571-35589110 (+)
CAST/EiJ MGP_CASTEiJ_G0002487
gene segment Chr6:38919012-38919550 (+)
CBA/J MGP_CBAJ_G0002501
gene segment Chr6:42145791-42146329 (+)
DBA/2J MGP_DBA2J_G0002505
gene segment Chr6:37614187-37614725 (+)
FVB/NJ MGP_FVBNJ_G0002533
gene segment Chr6:37387426-37387964 (+)
LP/J MGP_LPJ_G0002584
gene segment Chr6:39536396-39536934 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002508
gene segment Chr6:44390295-44390833 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002686
gene segment Chr6:38967638-38968176 (+)
PWK/PhJ MGP_PWKPhJ_G0002447
gene segment Chr6:37235804-37236342 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002399
gene segment Chr6:38676685-38677223 (+)
WSB/EiJ MGP_WSBEiJ_G0002503
gene segment Chr6:38909678-38910216 (+)



Homology
more
  • Human Ortholog
    TRBV2, T cell receptor beta variable 2
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRBV2, T cell receptor beta variable 2
  • Synonyms
    TCRBV22S1A2N1T, TCRBV2S1
  • Links
    NCBI Gene ID: 28620
    UniProt: A0A1B0GX68

  • Chr Location
    7q34; chr7:142300924-142301432 (+)  GRCh38

Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Sequences &
Gene Models
less
  • All Sequences
  • RefSeq
  • UniProt
Representative SequencesLengthStrain/SpeciesFlank
genomic 100039790 NCBI Gene Model | MGI Sequence Detail 431 C57BL/6J ±  kb
polypeptide A0A0A6YYE2 UniProt | EBI | MGI Sequence Detail 117 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
    IPR050413 T cell receptor beta variable
Molecular
Reagents
less
  • All nucleic 13
    Genomic 8
    cDNA 4
    Other 1
Other
Accession IDs
less
MGD-MRK-14882, MGI:3780592
References
more
  • Summaries
    All 13
    Gene Ontology 1
  • Earliest
    J:8182 Behlke MA, et al., Murine T-cell receptor mutants with deletions of beta-chain variable region genes. Proc Natl Acad Sci U S A. 1986 Feb;83(3):767-71
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory