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Trbv12-2 Gene Detail
Summary
  • Symbol
    Trbv12-2
  • Name
    T cell receptor beta, variable 12-2
  • Feature Type
    gene segment
  • IDs
    MGI:98601
    NCBI Gene: 100124674
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:41095798-41096298 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 19.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    139 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    5
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98601
 gene segment Chr6:41095785-41096298 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002583
 gene segment Chr6:39598942-39599455 (+)
A/J MGP_AJ_G0002554
 gene segment Chr6:37873269-37873782 (+)
AKR/J MGP_AKRJ_G0002545
 gene segment Chr6:39075865-39076378 (+)
BALB/cJ MGP_BALBcJ_G0002540
 gene segment Chr6:38085227-38085740 (+)
C3H/HeJ MGP_C3HHeJ_G0002507
 gene segment Chr6:39099260-39099773 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002681
 gene segment Chr6:40584418-40584931 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002250
 gene segment Chr6:35663625-35664166 (+)
CAST/EiJ MGP_CASTEiJ_G0002492
 gene segment Chr6:38989529-38990088 (+)
CBA/J MGP_CBAJ_G0002506
 gene segment Chr6:42219536-42220049 (+)
DBA/2J MGP_DBA2J_G0002510
 gene segment Chr6:37686350-37686863 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0002589
 gene segment Chr6:39611220-39611733 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002513
 gene segment Chr6:44470042-44470555 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002691
 gene segment Chr6:39051960-39052473 (+)
PWK/PhJ MGP_PWKPhJ_G0002452
 gene segment Chr6:37311514-37312019 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002404
 gene segment Chr6:38745428-38745980 (+)
WSB/EiJ MGP_WSBEiJ_G0002508
 gene segment Chr6:38982283-38982775 (+)



Homology
more
  • Human Ortholog
    TRBV13, T cell receptor beta variable 13
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRBV13, T cell receptor beta variable 13
  • Synonyms
    TCRBV13S1, TCRBV23S1A2T
  • Links
    NCBI Gene ID: 28574
    UniProt: A0A0A6YYD4

  • Chr Location
    7q34; chr7:142535809-142536292 (+)  GRCh38
  • Human Ortholog
    TRBV5-1, T cell receptor beta variable 5-1
  • Synonyms
    TCRBV5S1, TCRBV5S1A1T, TRBV51
  • Links
    NCBI Gene ID: 28614
    UniProt: A0A578

  • Chr Location
    7q34; chr7:142320677-142321544 (+)  GRCh38
  • Human Ortholog
    TRBV5-3, T cell receptor beta variable 5-3 (non-functional)
  • Synonyms
    TCRBV5S3, TCRBV5S5P, TRBV53
  • Links
    NCBI Gene ID: 28612
    UniProt: A0A0A0MS03

  • Chr Location
    7q34; chr7:142389202-142389668 (+)  GRCh38
  • Human Ortholog
    TRBV5-8, T cell receptor beta variable 5-8
  • Synonyms
    TCRBV5S4A2T, TCRBV5S8, TRBV58
  • Links
    NCBI Gene ID: 28607
    UniProt: A0A5A2

  • Chr Location
    7q34
Mutations,
Alleles, and
Phenotypes
less
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
Sequences &
Gene Models
less
  • All Sequences
    24
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124674 NCBI Gene Model | MGI Sequence Detail 501 C57BL/6J ±  kb
polypeptide A0A0B4J1H1 UniProt | EBI | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
    IPR050413 T cell receptor beta variable
Molecular
Reagents
less
  • All nucleic 11
    Genomic 8
    cDNA 2
    Other 1
Other
Accession IDs
less
MGD-MRK-14893
References
more
  • Summaries
    All 11
    Gene Ontology 1
  • Earliest
    J:7927 Sim GK, et al., V beta gene polymorphism and a major polyclonal T cell receptor idiotype. Cell. 1985 Aug;42(1):89-92
  • Latest
    J:164272 Giudicelli V, et al., IMGT/GENE-DB: a comprehensive database for human and mouse immunoglobulin and T cell receptor genes. Nucleic Acids Res. 2005 Jan 1;33(Database issue):D256-61
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory