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Trbv13-2 Gene Detail
Summary
  • Symbol
    Trbv13-2
  • Name
    T cell receptor beta, variable 13-2
  • Feature Type
    gene segment
  • IDs
    MGI:98608
    NCBI Gene: 100124675
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:41098330-41098766 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 19.20 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    17
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98608
 gene segment Chr6:41098330-41098766 (+)
129S1/SvImJ MGP_129S1SvImJ_G0002584
 gene segment Chr6:39601473-39601909 (+)
A/J MGP_AJ_G0002555
 gene segment Chr6:37875814-37876250 (+)
AKR/J MGP_AKRJ_G0002546
 gene segment Chr6:39078410-39078846 (+)
BALB/cJ MGP_BALBcJ_G0002541
 gene segment Chr6:38087772-38088208 (+)
C3H/HeJ MGP_C3HHeJ_G0002508
 gene segment Chr6:39101805-39102241 (+)
C57BL/6NJ MGP_C57BL6NJ_G0002682
 gene segment Chr6:40586963-40587399 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0002251
 gene segment Chr6:35666184-35666620 (+)
CAST/EiJ MGP_CASTEiJ_G0002493
 gene segment Chr6:38992073-38992509 (+)
CBA/J MGP_CBAJ_G0002507
 gene segment Chr6:42222063-42222499 (+)
DBA/2J MGP_DBA2J_G0002511
 gene segment Chr6:37688895-37689331 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0002590
 gene segment Chr6:39613765-39614201 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0002514
 gene segment Chr6:44472583-44473019 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0002692
 gene segment Chr6:39054503-39054939 (+)
PWK/PhJ MGP_PWKPhJ_G0002453
 gene segment Chr6:37314023-37314459 (+)
SPRET/EiJ MGP_SPRETEiJ_G0002405
 gene segment Chr6:38748003-38748439 (+)
WSB/EiJ MGP_WSBEiJ_G0002509
 gene segment Chr6:38984764-38985200 (+)



Homology
more
  • Human Ortholog
    TRBV10-1, T cell receptor beta variable 10-1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRBV10-1, T cell receptor beta variable 10-1
  • Synonyms
    TCRBV10S1, TCRBV12S2, TCRBV12S2A1T, TRBV101
  • Links
    NCBI Gene ID: 28585
    UniProt: A0A0K0K1A3

  • Chr Location
    7q34; chr7:142399860-142400377 (+)  GRCh38
  • Human Ortholog
    TRBV10-2, T cell receptor beta variable 10-2
  • Synonyms
    TCRBV10S2, TCRBV12S3, TRBV102
  • Links
    NCBI Gene ID: 28584
    UniProt: A0A0K0K1G8

  • Chr Location
    7q34; chr7:142424965-142425465 (+)  GRCh38
  • Human Ortholog
    TRBV10-3, T cell receptor beta variable 10-3
  • Synonyms
    TCRBV10S3, TCRBV12S1A1N2, TRBV103
  • Links
    NCBI Gene ID: 28583
    UniProt: A0A0K0K1G6

  • Chr Location
    7q34; chr7:142544212-142544685 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    2 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-in allele exhibit abnormal T cell differentiation.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    3
Sequences &
Gene Models
less
  • All Sequences
    31
  • RefSeq
    1
  • UniProt
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 100124675 NCBI Gene Model | MGI Sequence Detail 437 C57BL/6J ±  kb
transcript L37872 GenBank | ENA | DDBJ | MGI Sequence Detail 685 AKR/J  
polypeptide A0A140T8N6 UniProt | EBI | MGI Sequence Detail 113 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • InterPro Domains
    IPR007110 Immunoglobulin-like domain
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
    IPR050413 T cell receptor beta variable
Molecular
Reagents
less
  • All nucleic 18
    Genomic 5
    cDNA 12
    Other 1

    Microarray probesets 2
Other
Accession IDs
less
MGD-MRK-14900
References
more
  • Summaries
    All 20
    Gene Ontology 2
    Phenotypes 2
  • Earliest
    J:7995 Barth RK, et al., The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Nature. 1985 Aug 8-14;316(6028):517-23
  • Latest
    J:180175 Patel O, et al., Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19007-12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory