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Tcte1 Gene Detail
Summary
  • Symbol
    Tcte1
  • Name
    t-complex-associated testis expressed 1
  • Synonyms
    D17Sil1, Tcte-1
  • Feature Type
    protein coding gene
  • IDs
    MGI:98640
    NCBI Gene: 21645
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:45834360-45853605 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 22.54 cM, cytoband C
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    3
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98640
 protein coding gene Chr17:45834360-45853606 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023789
 protein coding gene Chr17:46539999-46560185 (+)
A/J MGP_AJ_G0023747
 protein coding gene Chr17:45425242-45444386 (+)
AKR/J MGP_AKRJ_G0023718
 protein coding gene Chr17:45734132-45757572 (+)
BALB/cJ MGP_BALBcJ_G0023751
 protein coding gene Chr17:45314761-45334373 (+)
C3H/HeJ MGP_C3HHeJ_G0023515
 protein coding gene Chr17:46446664-46469150 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024194
 protein coding gene Chr17:48551064-48571691 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021644
 protein coding gene Chr17:42221680-42241162 (+)
CAST/EiJ MGP_CASTEiJ_G0022996
 protein coding gene Chr17:46544608-46564699 (+)
CBA/J MGP_CBAJ_G0023491
 protein coding gene Chr17:50284303-50294809 (+)
DBA/2J MGP_DBA2J_G0023617
 protein coding gene Chr17:44215514-44235390 (+)
FVB/NJ MGP_FVBNJ_G0023584
 protein coding gene Chr17:43792770-43812051 (+)
LP/J MGP_LPJ_G0023698
 protein coding gene Chr17:47183909-47206397 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023613
 protein coding gene Chr17:49842993-49866748 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024239
 protein coding gene Chr17:46095749-46121822 (+)
PWK/PhJ MGP_PWKPhJ_G0022741
 protein coding gene Chr17:43522973-43543019 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022556
 protein coding gene Chr17:42963471-42982913 (+)
WSB/EiJ MGP_WSBEiJ_G0023061
 protein coding gene Chr17:46619258-46640265 (+)



Homology
more
  • Human Ortholog
    TCTE1, t-complex-associated-testis-expressed 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCTE1, t-complex-associated-testis-expressed 1
  • Synonyms
    D6S46, DRC5, FAP155
  • Links
    NCBI Gene ID: 202500
    neXtProt AC: NX_Q5JU00
    UniProt: Q5JU00

  • Chr Location
    6p21.1
Human Diseases
more
  • Diseases
    1 with Tcte1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit male sterility characterized by asthenozoospermia and decreased ATP generation within sperm.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 21645 NCBI Gene Model | MGI Sequence Detail 19246 C57BL/6J ±  kb
    transcript NM_013688 RefSeq | MGI Sequence Detail 3087 C57BL/6  
    polypeptide A6H639 UniProt | EBI | MGI Sequence Detail 498 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      Genomic 1
      cDNA 4
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-14943, MGD-MRK-14946, MGD-MRK-4780
    References
    more
    • Summaries
      All 38
      Diseases 1
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:8839 Rappold GA, et al., Identification of a testis-specific gene from the mouse t-complex next to a CpG-rich island. EMBO J. 1987 Jul;6(7):1975-80
    • Latest
      J:350511 Olszewska M, et al., Effects of Tcte1 knockout on energy chain transportation and spermatogenesis: implications for male infertility. Hum Reprod Open. 2024;2024(2):hoae020
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory