tip Gene Detail

Summary

• Symbol
  tip
• Name
  tippy

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98757
  NCBI Gene: 21864
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 9, Syntenic
• Mapping Data
  5 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  17 phenotypes from 1 allele in 1 genetic background
  1 images
  6 phenotype references
  

• All Mutations and Alleles
  1
• Spontaneous
  1
• Find Mice (IMSR)
  1 strains or lines available

Mice homozygous for this spontaneous mutation are small, hyperactive, cannot stand or walk without falling over, display occasional degenerating axons in the optic nerve, and rarely survive beyond 28 days of age.

Sequences &
Gene Models

• NCBI Gene
  21864

Other
Accession IDs

MGD-MRK-15117

References

• Summaries
  All 7

  Phenotypes 6
• Earliest
  J:4399 Porter BE, et al., S-laminin: mapping to mouse chromosome 9 and expression in the linked mutants tippy and ducky. Genomics. 1993 Apr;16(1):278-81
• Latest
  J:236593 Shih EK, et al., The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype. Cerebellum. 2015 Jun;14(3):292-307