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Tpbpa Gene Detail
Summary
  • Symbol
    Tpbpa
  • Name
    trophoblast specific protein alpha
  • Synonyms
    4311, clone 4311, Tb-1, Tb1, Tpbp
  • Feature Type
    protein coding gene
  • IDs
    MGI:98795
    NCBI Gene: 21984
  • Alliance
    genome feature page
  • Transcription Start Sites
    10 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:61086306-61089750 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.57 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    217 from dbSNP Build 142
  • Strain Annotations
    16
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98795
 protein coding gene Chr13:61086306-61089798 (-)
129S1/SvImJ ENSMUSG00200015474
 protein coding gene Chr13:58023321-58026813 (-)
A/J ENSMUSG00195042698
 protein coding gene Chr13:57480787-57484280 (-)
AKR/J ENSMUSG00220040126
 protein coding gene Chr13:56988889-56992381 (-)
BALB/cJ ENSMUSG00180014388
 protein coding gene Chr13:57700295-57703787 (-)
C3H/HeJ ENSMUSG00175033839
 protein coding gene Chr13:57486378-57489870 (-)
C57BL/6NJ ENSMUSG00215034850
 protein coding gene Chr13:57494083-57497575 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018622
 protein coding gene Chr13:56289030-56292643 (-)
CAST/EiJ no annotation
CBA/J ENSMUSG00210035204
 protein coding gene Chr13:57691200-57694692 (-)
DBA/2J ENSMUSG00185014463
 protein coding gene Chr13:58534290-58537782 (-)
FVB/NJ ENSMUSG00205028176
 protein coding gene Chr13:57306653-57310142 (-)
JF1/MsJ ENSUMUG00000009715
 protein coding gene Chr13:57879986-57883673 (-)
LP/J ENSMUSG00230027127
 protein coding gene Chr13:67896172-67899663 (-)
NOD/ShiLtJ ENSMUSG00190031890
 protein coding gene Chr13:57550150-57553642 (-)
NZO/HlLtJ ENSMUSG00225045565
 protein coding gene Chr13:61590334-61593826 (-)
PWK/PhJ ENSLUMG00010020754
 protein coding gene Chr13:56813442-56817129 (-)
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    1234
  • Tissues
    90
  • cDNA Data
    222
  • Literature Summary
    215
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 21984 NCBI Gene Model | MGI Sequence Detail 3445 C57BL/6J ±  kb
transcript NM_009411 RefSeq | MGI Sequence Detail 1573 ZRU/MplStud  
polypeptide P13438 UniProt | EBI | MGI Sequence Detail 124 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 270
    cDNA 224
    Primer pair 18
    Other 28
    Antibodies 4

    Microarray probesets 5
Other
Accession IDs
less
MGD-MRK-14724, MGD-MRK-14725, MGD-MRK-15177, MGI:2145390
References
more
  • Summaries
    All 254
    Developmental Gene Expression 215
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:386951 Guertin TM, et al., Onset of embryonic and placental defects coincide in 19 of 22 novel mid-gestation lethal murine knockout lines. Development. 2026 May 15;153(10):dev205276
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory