Tsz1 QTL Detail

Summary

• Symbol
  Tsz1
• Name
  thymus size 1
• Synonyms
  Tsz-1

• Feature Type
  QTL
• IDs
  MGI:98862
  NCBI Gene: 109642

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 5, cM position of peak correlated region/marker: Syntenic
• Mapping Data
  4 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype reference
  

• All Mutations and Alleles
  2
• QTL
  2
• Find Mice (IMSR)
  0 strains or lines available

This locus controls a 2X difference in thymus size relative to body size in mice >50 days of age. The dominant l allele determines large size in C57BL/6 and AKR; the s allele determines small size in A/J, DBA/2, BALB/c, CBA/J, C3H/He, 129/J, C57BL/10 andMA/My strains.

Sequences &
Gene Models

• NCBI Gene
  109642

Other
Accession IDs

MGD-MRK-15290, MGD-MRK-15291

References

• Summaries
  All 6

  Phenotypes 1
• Earliest
  J:7417 Peleg L, et al., Genetic control of thymus size in inbred mice. J Hered. 1984 Mar-Apr;75(2):126-30
• Latest
  J:97786 Miyazaki T, et al., Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice. Eur J Immunol. 2005 May;35(5):1510-20