Tthy Gene Detail

Summary

• Symbol
  Tthy
• Name
  thymocyte alloantigen

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98863
  NCBI Gene: 109873
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 12, Syntenic
• Mapping Data
  2 experiments

Mutations,
Alleles, and
Phenotypes

This locus controls antigen present on thymus-repopulating T-cells of bone marrow and fetal thymocytes. In adult thymus, Tpre and Tthy occur on overlapping T-cell populations. The d allele is found in C.AL-20, AKR, NZB and A/J; the a allele in BALB/c, C57BL/6, C57L, C3H/He, CBA/J, SWR, HRS and MRL.

Sequences &
Gene Models

• NCBI Gene
  109873

Other
Accession IDs

MGD-MRK-15293

References

• Summaries
  All 6
• Earliest
  J:6670 Owen FL, et al., Tthyd, a new thymocyte alloantigen linked to Igh-1. Implications for a switch mechanism for T cell antigen receptors. J Exp Med. 1982 Jan 1;155(1):52-60
• Latest
  J:7307 Owen FL, et al., Genes for the mouse T cell alloantigens Tpre, Tthy, Tind, and Tsu are closely linked near Igh on chromosome 12. J Exp Med. 1984 Jan 1;159(1):313-7