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Tyl Gene Detail
Summary
  • Symbol
    Tyl
  • Name
    trembly-like
  • Feature Type
    heritable phenotypic marker
  • IDs
    MGI:98877
    NCBI Gene: 103957
  • Alliance
Location &
Maps
more
  • Sequence Map
    Genome coordinates not available from the current reference assembly.
  • Genetic Map
    Chromosome X, Syntenic
  • Mapping Data
    7 experiments
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    1 phenotype reference
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Hemizygous males develop tremors, seizures, and paralysis in spite of normal of myelination and die prematurely. The life span of heterozygous mutant females is unaffected, though they exhibit mild tremors and become increasingly kyphotic with age.
Sequences &
Gene Models
less
Other
Accession IDs
less
MGD-MRK-15312
References
more
  • Summaries
    All 2
    Phenotypes 1
  • Earliest
    J:14294 Sweet HO, et al., Trembly-like (Tyl) - a new X-linked mutation in the mouse. Mouse Genome. 1990;87:112
  • Latest
    J:63103 Mouse Genome Database and National Center for Biotechnology Information, Entrez Gene Load. Database Release. 2000;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory