War Gene Detail

Summary

• Symbol
  War
• Name
  warfarin resistance

• Feature Type
  heritable phenotypic marker
• IDs
  MGI:98944
  NCBI Gene: 109735
• Alliance
  gene page

Location &
Maps

• Sequence Map
  Genome coordinates not available from the current reference assembly.

• Genetic Map
  Chromosome 7, Syntenic
• Mapping Data
  8 experiments

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from multigenic genotypes
  7 phenotype references
  

• All Mutations and Alleles
  1
• Chemically induced (other)
  1
• Find Mice (IMSR)
  0 strains or lines available

Heterozygotes for an allele found in a wild population exhibit greater resistance to a diet containing the anti-coagulant warfarin, with greater penetrance in females than in males.

Sequences &
Gene Models

• NCBI Gene
  109735

Other
Accession IDs

MGD-MRK-15428

References

• Summaries
  All 11

  Phenotypes 7
• Earliest
  J:220223 ROWE FP, et al., THE TOXICITY OF 0-025 PER CENT WARFARIN TO WILD HOUSE-MICE (MUS MUSCULUS L.). J Hyg (Lond). 1964 Sep;62:389-93
• Latest
  J:101681 Pelz HJ, et al., The genetic basis of resistance to anticoagulants in rodents. Genetics. 2005 Aug;170(4):1839-47