Zfp14 MGI Mouse Gene Detail - MGI:99160

Symbol

Zfp14
Name

zinc finger protein 14
Synonyms

4732429I09Rik, Krox-9, Zfp-14

Feature Type

protein coding gene
IDs

MGI:99160
NCBI Gene: 243906
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr7:29735784-29750805 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 17.26 cM
Mapping Data

1 experiment

SNPs within 2kb

624 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_99160	protein coding gene	Chr7:29735782-29751664 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0031996	protein coding gene	Chr7:28987764-28994175 (-)
A/J	MGP_AJ_G0031973	protein coding gene	Chr7:28240540-28246878 (-)
AKR/J	MGP_AKRJ_G0031906	protein coding gene	Chr7:28950662-28957015 (-)
BALB/cJ	MGP_BALBcJ_G0031980	protein coding gene	Chr7:28413399-28419740 (-)
C3H/HeJ	MGP_C3HHeJ_G0031699	protein coding gene	Chr7:29407066-29415195 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0032445	protein coding gene	Chr7:29931782-29940024 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029496	protein coding gene	Chr7:29270654-29277442 (-)
CAST/EiJ	MGP_CASTEiJ_G0031033	protein coding gene	Chr7:22639815-22646144 (-)
CBA/J	MGP_CBAJ_G0031665	protein coding gene	Chr7:31375424-31385261 (-)
DBA/2J	MGP_DBA2J_G0031817	protein coding gene	Chr7:27964568-27970915 (-)
FVB/NJ	MGP_FVBNJ_G0031774	protein coding gene	Chr7:28084988-28092228 (-)
LP/J	MGP_LPJ_G0031898	protein coding gene	Chr7:29322282-29328643 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031810	protein coding gene	Chr7:30642141-30648550 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032474	protein coding gene	Chr7:28439334-28445687 (-)
PWK/PhJ	MGP_PWKPhJ_G0030759	protein coding gene	Chr7:22996727-23003341 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0030592	protein coding gene	Chr7:19445286-19451859 (-)
WSB/EiJ	MGP_WSBEiJ_G0031143	protein coding gene	Chr7:28836705-28843381 (-)

Human Ortholog

ZFP14, ZFP14 zinc finger protein

Vertebrate Orthologs

6

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

ZFP14, ZFP14 zinc finger protein
Synonyms

ZNF531
Links

HGNC:29312

NCBI Gene ID: 57677

neXtProt AC: NX_Q9HCL3

UniProt: Q9HCL3
Chr Location

19q13.12; chr19:36334453-36379201 (-) GRCh38

MGI Vertebrate Homology

Zfp14 stringent orthology
1 human;1 mouse;5 zebrafish
HCOP

vertebrate homology predictions: ZFP14
Gene Tree

Zfp14

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Phenotype Summary

12 phenotypes from 2 alleles in 2 genetic backgrounds
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Endonuclease-mediated

3
Targeted

4
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

22 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

9
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

809
Tissues

55
cDNA Data

9
Literature Summary

6

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

64
RefSeq

26
UniProt

2
CCDS

CCDS39875.1

Ensembl

ENSMUSG00000053985 (Evidence)
NCBI Gene

243906

			Length	Strain/Species	Flank
genomic	ENSMUSG00000053985	Ensembl Gene Model \| MGI Sequence Detail	15022	C57BL/6J	± kb
transcript	ENSMUST00000207873	Ensembl \| MGI Sequence Detail	3411	Not Applicable
polypeptide	ENSMUSP00000146824	Ensembl \| MGI Sequence Detail	501	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000017633 zinc finger protein 14 homolog

(term hierarchy)
InterPro Domains

IPR050636 C2H2-type zinc finger domain-containing protein

IPR036051 KRAB domain superfamily

IPR001909 Krueppel-associated box

IPR036236 Zinc finger C2H2 superfamily

IPR013087 Zinc finger C2H2-type

IPR050758 Zinc finger protein, C2H2-type

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All nucleic 14

Genomic 4

cDNA 9

Primer pair 1

Microarray probesets 3

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MGD-MRK-11628, MGD-MRK-15857, MGD-MRK-15912, MGI:2442706

Summaries

All 37

Developmental Gene Expression 6

Gene Ontology 5

Phenotypes 9
Earliest

J:9172 Chavrier P, et al., Characterization of a mouse multigene family that encodes zinc finger structures. Mol Cell Biol. 1988 Mar;8(3):1319-26
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Zfp14:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr71685	Chr7:29750786-29750836 (-)	-6 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24